Thermo Fisher Scientific Phospho-FGFR4 (Tyr642) Polyclonal Antibody
FGFR4 Tyr642 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합. 인산화된 FGFR4의 내인성 발현 검출에 사용. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상 제품으로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 | — |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FGFR4 (Accession P22455), corresponding to amino acid residues around phosphorylated Tyr642. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816959 |
Product Specific Information
Antibody detects endogenous levels of FGFR4 only when phosphorylated at Tyr642.
Target Information
FGFR4 is a member of the FGFR family of receptor tyrosine kinases, which regulate cellular functions such as angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury.
The FGFR family is implicated in diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.
FGFR4 is required for normal down-regulation of CYP7A1 expression in response to FGF19 and plays a role in postnatal lung development and skeletal muscle cell lineage development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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