Thermo Fisher Scientific MYT1 Polyclonal Antibody
MYT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, Human, Mouse, Rat 시료에서 반응. Affinity Chromatography로 정제된 액상 항체로, PBS/glycerol 버퍼에 저장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 650–820 of human MYT1 (NP_004526.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804618 |
Product Specific Information
Immunogen sequence:
KPQDLPSKSV DIEVDENGTL DLSMHKHRKR ENAFPSSSSC SSSPGVKSPD ASQRHSSTSA PSSSMTSPQS SQASRQDEWD RPLDYTKPSR LREEEPEESE PAAHSFASSE ADDQEVSEEN FEERKYPGEV TLTNFKLKFL SKDIKKELLT CPTPGCDGSG HITGNYASHR S
Positive Samples:
U-87MG, U-251MG, Mouse liver, Mouse kidney, Rat kidney, Rat liver
Cellular Location:
Nucleus
Target Information
The protein encoded by this gene is a member of a family of neural-specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), thereby negatively regulating the cell cycle G2/M transition. It remains membrane-associated throughout the cell cycle and is tightly regulated. Protein kinases AKT1/PKB and PLK (Polo-like kinase) phosphorylate and regulate its activity. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to promoter regions of proteolipid proteins in the central nervous system and plays a role in nervous system development.
Safety and Regulatory Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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