Thermo Fisher Scientific MYT1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
KPQDLPSKSV DIEVDENGTL DLSMHKHRKR ENAFPSSSSC SSSPGVKSPD ASQRHSSTSA PSSSMTSPQS SQASRQDEWD RPLDYTKPSR LREEEPEESE PAAHSFASSE ADDQEVSEEN FEERKYPGEV TLTNFKLKFL SKDIKKELLT CPTPGCDGSG HITGNYASHR S

Positive Samples:
U-87MG, U-251MG, Mouse liver, Mouse kidney, Rat kidney, Rat liver

Cellular Location:
Nucleus

Target Information

The protein encoded by this gene is a member of a family of neural-specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), thereby negatively regulating the cell cycle G2/M transition. It remains membrane-associated throughout the cell cycle and is tightly regulated. Protein kinases AKT1/PKB and PLK (Polo-like kinase) phosphorylate and regulate its activity. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to promoter regions of proteolipid proteins in the central nervous system and plays a role in nervous system development.

Safety and Regulatory Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.