Thermo Fisher Scientific MYT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 650-820 of human MYT1 (NP_0045261) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYT1,uniProtId:Q01538-1,ncbiNodeId:9606,antigenRange:650-820,antigenLength:1121,antigenImageFileName:PA5-88052_MYT1_Q01538-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88052_MYT1_Q01538-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.68 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804618

Product Specific Information

Immunogen sequence: KPQDLPSKSV DIEVDENGTL DLSMHKHRKR ENAFPSSSSC SSSPGVKSPD ASQRHSSTSA PSSSMTSPQS SQASRQDEWD RPLDYTKPSR LREEEPEESE PAAHSFASSE ADDQEVSEEN FEERKYPGEV TLTNFKLKFL SKDIKKELLT CPTPGCDGSG HITGNYASHR S; Positive Samples: U-87MG, U-251MG, Mouse liver, Mouse kidney, Rat kidney, Rat liver; Cellular Location: Nucleus

Target Information

The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.