Thermo Fisher Scientific HLA-DQA1/DQA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (QGLRSVGASRH) corresponding to the C-terminus amino acids of HLA-DQA2 (aa 241-251). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HLA-DQA1/DQA2,uniProtId:P01906-1,ncbiNodeId:9606,antigenRange:241-251,antigenLength:255,antigenImageFileName:PA5-19388_HLA-DQA1DQA2_P01906-1_Goat.svg,antigenImageFileNamePDP:PA5-19388_HLA-DQA1DQA2_P01906-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10984364

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Target Information

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.