Thermo Fisher Scientific BCL2A1 Polyclonal Antibody
BCL2A1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot에 적합하며 인간 시료에 반응합니다. 액상 형태로 제공되며 TBS 버퍼에 보존됩니다. 세포 생존 및 아포토시스 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (NVVSVDTART) corresponding to internal amino acids of BCL2A1 (aa 60–70) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986081 |
Product Specific Information
- Predicted to react with bovine, canine, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family. These proteins form hetero- or homodimers and act as anti- and pro-apoptotic regulators involved in various cellular processes such as embryonic development, homeostasis, and tumorigenesis.
The encoded protein reduces the release of pro-apoptotic cytochrome c from mitochondria and blocks caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by extracellular signals such as GM-CSF, CD40, phorbol ester, TNF, and IL-1, suggesting a cytoprotective function essential for lymphocyte activation and cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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