Thermo Fisher Scientific ARTS Polyclonal Antibody
Human ARTS 단백질을 표적으로 하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB, IHC, Flow Cytometry에 적합합니다. 액상형 비결합 항체이며, 0.5 mg/mL 농도로 제공됩니다. 세포 사멸 관련 연구용으로 사용됩니다.
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- PA519389
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RNKLTRESGTD) corresponding to internal amino acids of 38231 (aa 425–435) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11000623 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis.
ARTS (Apoptosis Related Protein in TGF-beta Signaling Pathway) is a mitochondrial septin-like protein encoded by the human septin H5/PNUTL2/CDCrel2b gene. It localizes to mitochondria and translocates to the nucleus during apoptosis.
ARTS is expressed in various tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents such as TNF-α and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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