Thermo Fisher Scientific GCAP2 Monoclonal Antibody (A1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

ELISA (ELISA)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Published species

Bovine

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

A1

Immunogen

Bacterial expressed full length GCAP-2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GCAP2,uniProtId:P51177-1,ncbiNodeId:9913,antigenRange:1-204,antigenLength:204,antigenImageFileName:MA1-725_GCAP2_P51177-1_House_mouse.svg,antigenImageFileNamePDP:MA1-725_GCAP2_P51177-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2263831

Product Specific Information

MA1-725 detects GCAP-2 from bovine samples. This antibody is specific for GCAP-2 and does not react with other isotypes.

MA1-725 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~23 kDa protein representing GCAP-2 protein in bovine samples.

The MA1-725 immunogen is bacterial expressed full length GCAP-2.

Target Information

Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.