
Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
NeuroD1 단백질을 검출하기 위한 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도. 신경분화 및 MODY6 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEUROD1 (Accession Q13562), corresponding to amino acid residues M1–D31 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854534 |
Product Specific Information
Antibody detects endogenous levels of total NEUROD1.
Target Information
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It binds to the insulin gene E-box and requires dimerization with another bHLH protein for efficient DNA binding.
Defects in NEUROD1 cause maturity onset diabetes of the young type VI (MODY6), a non-insulin-dependent diabetes mellitus with autosomal dominant inheritance, early onset, and impaired insulin secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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