
Thermo Fisher Scientific H4K8ac Polyclonal Antibody, ChIP-Verified
ChIP 검증된 H4K8ac 폴리클로날 항체로, Western blot, ICC/IF, ChIP, Peptide Array에 적합합니다. 인간, 마우스, 랫 등 다양한 종에서 반응하며, 항원 친화 크로마토그래피로 정제된 액상 제품입니다. 다른 아세틸화 히스톤과 교차 반응하지 않습니다.
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Thermo Fisher Scientific H4K8ac Polyclonal Antibody, ChIP-Verified
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| ChIP assay (ChIP) | 1.5 µg/1×10⁶ cells |
| Peptide Array (Array) | 1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | C. elegans, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic acetylated peptide corresponding to residues surrounding Lys8 of human histone H4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986044 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other acetylated histones.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction. The H4 gene is intronless, encodes a histone H4 family member, and is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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