Thermo Fisher Scientific Cyclin C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20

-

Immunocytochemistry (ICC/IF)

2 µg/mL

-

Immunoprecipitation (IP)

10 µg/mg protein lysate

-

Product Specifications

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10982613

Product Specific Information

PA5-16227 targets Cyclin C in immunofluorescence, immunoprecipitation, and Western blot applications and shows reactivity with Canine, Human, mouse, and Rat samples.

The PA5-16227 immunogen is a synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C.

Target Information

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.