Thermo Fisher Scientific Cyclin C Polyclonal Antibody
Cyclin C 단백질을 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. Canine, Human, Mouse, Rat 시료에서 반응. 합성 펩타이드 면역원 기반, 4°C 보관, 연구용 전용.
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- PA516227
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20 | - |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
| Immunoprecipitation (IP) | 10 µg/mg protein lysate | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Not Applicable |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_10982613 |
Product Specific Information
PA5-16227 targets Cyclin C in immunofluorescence, immunoprecipitation, and Western blot applications and shows reactivity with Canine, Human, Mouse, and Rat samples.
The PA5-16227 immunogen is a synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C.
Target Information
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knockout of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk8, a novel protein kinase of the cdk family. It is suggested that Cyclin C and cdk8 control RNA polymerase II function. Human cdk8–Cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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