Thermo Fisher Scientific FIP1 Polyclonal Antibody
FIP1L1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 인체 반응성 확인 및 오랑우탄과 교차 반응 예측. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human factor interacting with PAP (FIP1L1, UniProt ID: Q6UN15-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3′-end formation. It recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase and other factors to promote cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition, stimulates poly(A) addition, and binds to U-rich RNA sequence elements surrounding the poly(A) site. It may act to tether poly(A) polymerase to the CPSF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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