Thermo Fisher Scientific FIP1 Polyclonal Antibody
FIP1L1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합. 액상 형태로 제공되며 4°C 보관. FFPE 조직에서 citrate buffer(pH 6.0) 전처리 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FIP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 544 and 594 of human factor interacting with PAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation. It recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase and other factors to facilitate cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition by binding to U-rich RNA sequence elements surrounding the poly(A) site. It may act to tether poly(A) polymerase to the CPSF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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