Thermo Fisher Scientific Cytokeratin 20 Monoclonal Antibody (Ks 20.8)
인간 조직에서 Cytokeratin 20을 검출하는 Mouse monoclonal antibody입니다. 다양한 IHC 및 WB 응용에 적합하며, 파라핀 및 동결 조직에서 사용 가능합니다. 단백질 구조 연구 및 세포 분화 연구에 활용됩니다. 2–8°C에서 보관하며 Wet ice로 배송됩니다.
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Thermo Fisher Scientific Cytokeratin 20 Monoclonal Antibody (Ks 20.8)
Applications 및 Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | 3 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:20–1:50 | - |
| Immunohistochemistry – Free Floating (IHC (Free)) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Ks 20.8 |
| Immunogen | Purified cytokeratin 20 from human intestinal mucosa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage conditions | 2–8°C |
| Shipping conditions | Wet ice |
| RRID | AB_1076310 |
Product Specific Information
For IHC applications, pretreatment with protease is recommended.
Target Information
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins.
Type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Cytokeratin 20 is a major cellular protein of mature enterocytes and goblet cells, specifically expressed in the gastric and intestinal mucosa.
The type I cytokeratin genes are clustered in a region of chromosome 17q12–q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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