Thermo Fisher Scientific TP53INP2 Polyclonal Antibody
TP53INP2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보존되어 장기 안정성이 우수합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 148–193 of Human TP53INP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719656 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220-amino-acid nuclear protein expressed in developing murine brain and spinal cord, as well as in sensory and motor neuron tracts of the peripheral nervous system.
It participates in mammalian cell autophagy, translocating from the nucleus to autophagosome structures upon activation by rapamycin or starvation.
TP53INP2 is essential for autophagosome development and functions as a scaffold protein, recruiting LC3 and LC3-related proteins such as GABARAP and GABARAP-like2 to the autophagosome membrane via interaction with TMEM49.
The TP53INP2 gene is located on human chromosome 20, which constitutes approximately 2% of the human genome and encodes over 600 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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