Thermo Fisher Scientific CD163 Monoclonal Antibody (eBioGHI/61 (GHI/61)), Super Bright 600, eBioscience
인간 CD163 단백질을 인식하는 마우스 단클론 항체로, Super Bright 600 형광체가 결합된 형광세포분석용 시약입니다. 대식세포 및 단핵세포 표지에 적합하며, 405 nm 레이저로 여기되어 600 nm에서 방출됩니다. 4℃ 암소 보관, 동결 금지.
- 카탈로그번호
- 63-1639-4x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD163 Monoclonal Antibody (eBioGHI/61 (GHI/61)), Super Bright 600, eBioscience
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Flow Cytometry (Flow) | 5 µL (1.0 µg)/test | View 15 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Super Bright™ 600, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioGHI/61 (GHI/61) |
| Conjugate | Super Bright™ 600 |
| Excitation/Emission Max | 414 / 601 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Wet ice |
| RRID | AB_2744845 |
Additional Formats
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 700
- APC
- Biotin
- Brilliant Violet 421
- Brilliant Violet 711
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 645
- Request custom conjugation
Product Specific Information
The eBioGHI/61 monoclonal antibody reacts with human CD163 (Haemoglobin Scavenger Receptor, M130), a macrophage scavenger receptor family member. CD163 is expressed by tissue macrophages, circulating blood monocytes, and may also be expressed by hematopoietic progenitor cells. It functions as a high-affinity scavenger receptor for the hemoglobin–haptoglobin complex, clearing hemoglobin from the blood. Upon ligand binding, CD163 initiates signaling leading to IL-6 and IL-10 production.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-diluted and validated for flow cytometry at 5 µL (1.0 µg)/test
- Laser: Violet (405 nm); Emission: 600 nm
- Recommended filter: 610/20 bandpass
Super Bright 600 is a tandem dye sensitive to photo-induced oxidation; protect from light.
When using multiple Super Bright dyes, use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize non-specific interactions.
Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days at 4°C in the dark.
Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.
Target Information
CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, member of the scavenger receptor cysteine-rich superfamily, and receptor for the hemoglobin–haptoglobin complex. It protects tissues from oxidative damage and may be involved in iron recycling. CD163 is expressed on monocytes and macrophages, upregulated by IL-10, IL-6, and dexamethasone, and shed by LPS or PMA stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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