Thermo Fisher Scientific TRPV4 Polyclonal Antibody

Thermo Fisher Scientific TRPV4 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid multiple freeze–thaw cycles.
Centrifuge all antibody preparations before use (10000 × g, 5 min).

Target Information

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It is a non-selective calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the TRP superfamily.
Mutations in the TRPV4 gene are associated with spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC.
Diseases linked to TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type.
Multiple transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.