Thermo Fisher Scientific NFKBID Polyclonal Antibody
NFKBID 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ELISA에 적합합니다. 인간 시료 반응성이며 항원 친화 크로마토그래피로 정제되었습니다. 염증 반응 및 NF-kappa-B 조절 연구에 활용됩니다.
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Thermo Fisher Scientific NFKBID Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
| ELISA | 1:2,000–1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from 1–221 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2635148 |
Product Specific Information
The antibody detects endogenous levels of total NFKBID protein.
Target Information
NFKBID may regulate the expression of IL-2, IL-6, and other cytokines through modulation of NF-kappa-B activity. It plays a role in the regulation of inflammatory responses and may control TCR-induced negative selection of thymocytes.
I-kappa-BNS, encoded by Nfkbid, is essential for the development of marginal zone and peritoneal B-1 B cells and for extrafollicular antibody responses to T-independent and T-dependent immunogens.
I-kappa-BNS functions as a member of the I-kappa-B family of NF-kappa-B inhibitors, induced upon TCR signaling, and mediates both positive and negative gene regulation depending on cell type and cytokine context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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