Thermo Fisher Scientific KV1.1 (KCNA1) (extracellular) Polyclonal Antibody, Atto 594

Applications

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 1:100

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:25

Product Specifications

Product Specific Information

Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

This gene encodes a voltage-gated delayed potassium channel related to the Drosophila Shaker channel.
The protein has six transmembrane segments; the loop between S5 and S6 forms the pore with a conserved selectivity filter motif.
The functional channel is a homotetramer.
The N-terminus associates with beta subunits that affect inactivation and expression, while the C-terminus binds PDZ domain proteins responsible for channel targeting.
Mutations in this gene are linked to myokymia with periodic ataxia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: APC-161-AR-50UL_KV1.1_KCNA1_P10499-1_Rabbit_PDP.jpeg, APC-161-AR-50UL_KV1.1_KCNA1_P10499-1_Rabbit.svg)