Thermo Fisher Scientific GPR55 Polyclonal Antibody
인간 GPR55 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 5–10 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 PBS 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from 3rd extracellular domain of human GPR55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2112843 |
Product Specific Information
By immunohistochemistry, OPA1-15577 detects GPR55 in formalin-fixed, paraffin-embedded human tissues.
Target Information
GPR55 is expressed in the brain, with mRNA transcripts detected in the caudate nucleus and putamen, but not in five other brain regions (Sawzdargo et al., 1999). ESTs have been isolated from liver/spleen libraries.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a structural motif of seven membrane-spanning helices and existing in both active and inactive forms. Various ligands activate GPCRs, leading to signaling via G-proteins and downstream effectors. Negative regulation of GPCRs plays a crucial role in cellular physiology and pharmacological research. GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) are examples of successful therapeutics in this category.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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