Thermo Fisher Scientific AVPR1B Polyclonal Antibody
Human AVPR1B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. Antigen affinity chromatography로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. AVPR1B 관련 신호전달 연구용으로 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human AVPR1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2062249 |
Product Specific Information
OPA1-15268 detects V1B from human samples.
Target Information
Vasopressin V1B receptor expression has been observed in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
G-protein Coupled Receptors (GPCRs) are one of the largest families of signaling molecules, sharing a structural motif of seven membrane-spanning helices and existing in both active and inactive forms.
They are activated by various ligands leading to downstream signaling via G-proteins and effectors.
GPCR regulation mechanisms are key to understanding cellular physiology and have driven the development of major pharmaceuticals such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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