Thermo Fisher Scientific VASP Polyclonal Antibody
VASP 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 등 다양한 응용에 적합하며, 인간 및 생쥐 반응성. 고순도 정제, 액상 형태로 제공되며 안정적인 저장 조건을 갖춤.
- 카탈로그번호
- PA5143220
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RKVSKQEEASGGPT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933859 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. These proteins contain an EHV1 N-terminal domain that binds proteins with E/DFPPPPXD/E motifs, targeting Ena-VASP proteins to focal adhesions. The mid-region has a proline-rich domain that interacts with SH3 and WW domain-containing proteins, while the C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and plays a role in cell adhesion and motility, as well as intracellular signaling pathways regulating integrin–extracellular matrix interactions. VASP activity is regulated by cyclic nucleotide-dependent kinases PKA and PKG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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