Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI1E5), TrueMAB

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation. BTLA is expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells, but not on Th2 cells.
BTLA interacts with HVEM (Herpesvirus Entry Mediator), a TNF receptor superfamily member, forming a critical pathway that modulates lymphocyte activation and immune homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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