Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI1E5), TrueMAB
Human BTLA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. Lyophilized 형태이며 PBS buffer에 trehalose 포함. 연구용으로 면역반응 조절 연구 및 BTLA 관련 세포 분석에 활용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 31-157 + Mouse Fc of human BTLA produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor, regulating immune responses by inhibiting lymphocyte activation. BTLA is expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells, but not on Th2 cells.
BTLA interacts with HVEM (Herpesvirus Entry Mediator), a TNF receptor superfamily member, forming a critical pathway that modulates lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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