Thermo Fisher Scientific SPNS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

Immunohistochemistry (IHC)

2.5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

18 amino acid peptide near the amino terminus of human SPINSTER if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPNS1,uniProtId:Q9H2V7-1,ncbiNodeId:9606,antigenRange:1,antigenLength:528,antigenImageFileName:PA5-38050_SPNS1_Q9H2V7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-38050_SPNS1_Q9H2V7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2554654

Product Specific Information

A recommended positive control is human placenta tissue lysate.

At least four isoforms of SPINSTER are known to exist. This antibody is not expected to cross-react with other members of the spinster family of proteins.

Target Information

SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.