Thermo Fisher Scientific DOCK8 Polyclonal Antibody
Western blot과 IHC(P)에서 검증된 DOCK8 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 형태. 냉장 또는 냉동 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 17 amino acid peptide near the carboxy terminus of human DOCK8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554653 |
Product Specific Information
- A recommended positive control is EL4 cell lysate.
- Multiple isoforms of DOCK8 are known to exist.
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse.
Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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