Thermo Fisher Scientific IL-3 Monoclonal Antibody, PeproTech

Applications and Tested Dilution

Product Specifications

Product Specific Information

Amino Acid Sequence of Recombinant Protein:
APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF.

Preparation:
Produced in mice immunized with highly pure Recombinant Human IL-3. The anti-Human IL-3-specific antibody was purified from tissue culture supernatant by Protein G affinity chromatography.

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and IL-3 bioactivity is highly species-specific (e.g., human IL-3 has no activity on mouse cells).
IL-3 is a potent growth-promoting cytokine capable of supporting proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis. It also possesses neurotrophic activity and may be associated with neurological disorders.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.