Thermo Fisher Scientific Cyclin D3 Polyclonal Antibody
Cyclin D3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 세포주기 조절 관련 연구에 유용합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 201–292 of human Cyclin D3 (NP_001751.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804202 |
Product Specific Information
- Immunogen sequence:
SMIATGSIGA AVQGLGACSM SGDELTELLA GITGTEVDCL RACQEQIEAA LRESLREASQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI HL - Positive Samples: HeLa, K-562, Mouse spleen
- Cellular Location: Cytoplasm, Membrane, Nucleus
Target Information
The protein encoded by this gene belongs to the highly conserved cyclin family, characterized by periodic changes in protein abundance through the cell cycle. Cyclins regulate CDK kinases and form complexes with CDK4 or CDK6, essential for G1/S transition. Cyclin D3 is involved in phosphorylation of tumor suppressor protein Rb and is necessary for G2 phase progression after UV exposure. Multiple transcript variants exist.
Diseases associated with CCND3 include Retinoblastoma and Plasma Cell Leukemia.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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