Thermo Fisher Scientific CDK2 Polyclonal Antibody
Thermo Fisher Scientific의 CDK2 Polyclonal Antibody는 인간 CDK2 단백질에 특이적이며 WB, ELISA, IP 등 다양한 응용에 적합합니다. Rabbit IgG 폴리클로날 형태로, 보존제가 없고 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 권장됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:1,000–1:2,000 |
| Immunoprecipitation (IP) | 2–4 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CDK2 protein (Met1–Leu298) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787773 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CDK2/p33.
Target Information
CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO is a specific isoform of the UNG gene, localized exclusively in the nucleus and exhibiting uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during the G1 phase and are turned over during the cell cycle. Cyclin A–CDK2 levels peak at the G1/S transition, and both are associated with DNA in the initiation complex during replication. Rb protein acts as a substrate for CDK2–Cyclin E and/or CDK2–Cyclin A in vivo. CDK2 is activated and localized to the nucleus during late G1, S, and G2 phases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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