Thermo Fisher Scientific Cytokeratin 6 Monoclonal Antibody (ZY14)
사람 세포에서 Cytokeratin 6을 검출하는 Mouse IgG1 단클론 항체. Western blot 및 파라핀 IHC에 적합. 단백질 A로 정제된 액상 형태로 제공되며 0.5 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific Cytokeratin 6 Monoclonal Antibody (ZY14)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZY14 |
| Immunogen | A synthetic peptide of human Cytokeratin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Esophagus
- Cellular location: Cytoplasm
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (hyperproliferation-related keratins).
Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, including epidermis, in both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas, and its expression is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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