Thermo Fisher Scientific Cytokeratin 6 Monoclonal Antibody (LP34)
인체 유래 Cytokeratin 6을 인식하는 마우스 모노클로날 항체로, Western blot 및 파라핀 포매 조직 면역조직화학에 적합합니다. 단백질 A로 정제된 액상 항체이며, 세포질 내 케라틴 6 발현 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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- pk
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Applications 및 권장 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LP34 |
| Immunogen | A synthetic peptide of human Cytokeratin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Esophagus
- Cellular location: Cytoplasm
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins.
Keratin 6 is present in hair follicles and suprabasal cells of various internal stratified epithelia, as well as in the epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes, leading to expression of CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with cellular differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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