Thermo Fisher Scientific TFB1M Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TFB1M. Recombinant protein control fragment (Product #RP-102224). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TFB1M,uniProtId:Q8WVM0-1,ncbiNodeId:9606,antigenRange:192-317,antigenLength:346,antigenImageFileName:PA5-56142_TFB1M_Q8WVM0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56142_TFB1M_Q8WVM0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648408

Product Specific Information

Immunogen sequence: QRSRLSVMAQ YLCNVRHIFT IPGQAFVPKP EVDVGVVHFT PLIQPKIEQP FKLVEKVVQN VFQFRRKYCH RGLRMLFPEA QRLESTGRLL ELADIDPTLR PRQLSISHFK SLCDVYRKMC DEDPQL

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

Target Information

The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.