Thermo Fisher Scientific TFB1M Polyclonal Antibody
Human TFB1M 단백질을 인식하는 Rabbit polyclonal antibody로서, WB 및 IHC(P) 분석에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 미토콘드리아 전사 및 rRNA 메틸화 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: [References not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TFB1M. Recombinant protein control fragment (Product #RP-102224). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648408 |
Product Specific Information
- Immunogen sequence:
QRSRLSVMAQ YLCNVRHIFT IPGQAFVPKP EVDVGVVHFT PLIQPKIEQP FKLVEKVVQN VFQFRRKYCH RGLRMLFPEA QRLESTGRLL ELADIDPTLR PRQLSISHFK SLCDVYRKMC DEDPQL - Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 89%
Target Information
The protein encoded by the TFB1M gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. It is part of the basal mitochondrial transcription complex and is essential for mitochondrial gene expression. Methylation and transcriptional activities are independent. Variations in this gene may affect aminoglycoside-induced deafness severity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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