Thermo Fisher Scientific SEMA3E Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SEMA3E if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SEMA3E,uniProtId:O15041-1,ncbiNodeId:9606,antigenRange:635-767,antigenLength:775,antigenImageFileName:PA5-56140_SEMA3E_O15041-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56140_SEMA3E_O15041-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647106

Product Specific Information

Immunogen sequence: MDLGLLFLRL HKSDAGTYFC QTVEHSFVHT VRKITLEVVE EEKVEDMFNK DDEEDRHHRM PCPAQSSISQ GAKPWYKEFL QLIGYSNFQR VEEYCEKVWC TDRKRKKLKM SPSKWKYANP QEKKLRSKPE HYR

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

Target Information

The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved approximately 400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.