Thermo Fisher Scientific SEMA3E Polyclonal Antibody
Rabbit polyclonal antibody targeting human SEMA3E recombinant protein. Suitable for research use in axon guidance and immune regulation studies. Supplied as liquid form, unconjugated, 0.1 mg/mL concentration. Store at 4°C short term or -20°C for long t...
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Thermo Fisher Scientific SEMA3E Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEMA3E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647106 |
Product Specific Information
Immunogen sequence:
MDLGLLFLRL HKSDAGTYFC QTVEHSFVHT VRKITLEVVE EEKVEDMFNK DDEEDRHHRM PCPAQSSISQ GAKPWYKEFL QLIGYSNFQR VEEYCEKVWC TDRKRKKLKM SPSKWKYANP QEKKLRSKPE HYR
Highest antigen sequence identity:
- Mouse: 86%
- Rat: 86%
Target Information
Semaphorins constitute the largest family of axon guidance cues described to date. They are divided into eight classes, with classes 3–7 found in vertebrates.
- Class 3 Semaphorins: Secreted proteins
- Classes 4–6: Transmembrane proteins
- Class 7: Membrane-associated via GPI linkage
Semaphorins possess a conserved ~400 amino acid sema domain and are known as collapsing factors and mediators of axon repulsion, while also functioning as context-dependent chemoattractants.
They play roles in cardiovascular development and immune cell antigen presentation.
Receptors mediating semaphorin signaling include Neuropilin and Plexin family proteins.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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