Thermo Fisher Scientific CHRNA3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CHRNA3 protein. Recombinant immunogen-based for high specificity. Suitable for neurotransmission and receptor studies. Supplied as liquid form, 0.1 mg/mL concentration, stored at 4°C or -20°C. For research use...
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Thermo Fisher Scientific CHRNA3 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHRNA3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639795 |
Product Specific Information
Immunogen sequence:
RTPTTHTMPS WVKTVFLNLL PRVMFMTRPT SNEGNAQKPR PLYGAELSNL NCFSRAESKG CKEGYPCQDG MCGYCHHRRI KISNFSANLT RSSSSESVDA VLSLSALSPE IKEAIQSVKY IAENMKAQNE AKEIQDDWKY VAM
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. These proteins form pentameric complexes composed of alpha and beta subunits. The CHRNA3 gene encodes an alpha-type subunit characterized by adjacent cysteine residues. The encoded protein functions as a ligand-gated ion channel involved in neurotransmission. Gene polymorphisms are associated with increased risk of smoking initiation and lung cancer susceptibility. Alternatively spliced transcript variants have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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