Thermo Fisher Scientific TCP-1 theta Polyclonal Antibody
TCP-1 theta 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에서 반응합니다. Western blot, IHC(P), ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TCP-1 theta. Recombinant protein control fragment (Product #RP-91818). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648329 |
Product Specific Information
Immunogen sequence:
VYSCPFDGMI TETKGTVLIK TAEELMNFSK GEENLMDAQV KAIADTGANV VVTGGKVADM ALHYANKYNI MLVRLNSKWD LRRLCKTVGA TALPRLTPPV LEEMGHCDSV YLSEVGDTQV VV
- Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 98%
Target Information
TCP-1 theta is the theta subunit of the CCT (chaperonin containing TCP1 complex) chaperonin molecule, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins.
Molecular chaperones assist in protein folding upon ATP hydrolysis, and TCP-1 theta may play a role in the assembly of the BBsome, a complex involved in ciliogenesis and vesicle transport to the cilia.
It is also involved in the folding of actin and tubulin. The intact CCT complex is composed of eight polypeptides in a double ring structure and is important in folding the VHL tumor suppressor protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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