Thermo Fisher Scientific Orexin A Polyclonal Antibody
Human Orexin A를 인식하는 sheep polyclonal antibody로, IHC(P), IHC(F), ELISA 등에 사용 가능. Hypothalamus 조직에서 양성 대조로 활용 가능하며, 수면·각성 관련 연구에 적합. 5 mg/mL 농도, PBS buffer, sodium azide 포함, 장기 보관은 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
ELISA
- 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids P(2) L P D C C R Q K T C S C(14) of human orexin A conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2117626 |
Product Specific Information
- Predicted to react with bovine, chimpanzee, dog, horse, mouse, pig, rabbit, rat, and rhesus monkey based on sequence homology.
- Hypothalamus tissue can be used as a positive control.
- Sheep anti-human orexin A antibody recognizes human orexin A, an excitatory neuropeptide linked to alertness and wakefulness in humans.
Target Information
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, functioning in the regulation of sleep and arousal. This neuropeptide system may also play a role in feeding behavior, metabolism, and homeostasis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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