Thermo Fisher Scientific Phospho-hnRNP K (Ser284) Polyclonal Antibody
인산화 hnRNP K (Ser284)를 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 인간·마우스·랫트 반응성. 고순도(>95%) 항원 친화 크로마토그래피 정제, 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human hnRNP K around the phosphorylation site of Serine 284 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553750 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 51 kDa.
- Purity >95% by SDS-PAGE.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). They are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm.
The protein encoded by this gene is located in the nucleoplasm and contains three KH domains that bind RNAs. It uniquely binds poly(C) sequences and may play a role in cell cycle progression.
Several alternatively spliced transcript variants have been described for this gene, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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