Thermo Fisher Scientific Phospho-IFNGR1 (Tyr457) Polyclonal Antibody
Phospho-IFNGR1 (Tyr457) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 사용 가능. Western blot에 최적화된 고순도 항체로, IFNGR1의 인산화 부위를 특이적으로 인식. 연구용으로 면역 반응 및 신호전달 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human IFN-γRα around the phosphorylation site of Tyrosine 457 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553751 |
Product Specific Information
- Detects endogenous protein at molecular weights of 54 and 90 kDa.
- Purity >95% by SDS-PAGE.
Target Information
The IFNGR1 gene encodes the ligand-binding alpha chain of the gamma interferon receptor.
The human interferon-gamma receptor is a heterodimer consisting of IFNGR1 and IFNGR2.
Genetic variations in IFNGR1 are associated with susceptibility to Helicobacter pylori infection.
Defects in IFNGR1 can cause Mendelian susceptibility to mycobacterial disease (familial disseminated atypical mycobacterial infection).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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