Thermo Fisher Scientific Cytokeratin 17 Recombinant Rabbit Monoclonal Antibody (RM351)
Cytokeratin 17 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM351 |
| Immunogen | A peptide corresponding to residues in human Cytokeratin 17 (CK-17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744962 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best production candidates.
Recombinant antibodies offer:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Cytokeratins are intermediate filament proteins exhibiting biochemical diversity across human epithelial tissues, represented by at least 20 different polypeptides.
They range in molecular weight from approximately 40 kDa to 68 kDa and have isoelectric points between pH 4.9–7.8.
Cytokeratin expression patterns help distinguish epithelial malignancies, making cytokeratin antibodies valuable tools in:
- Differential diagnosis of tumors (immunohistochemistry)
- Cytopathology
- Flow cytometric assays
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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