Thermo Fisher Scientific CD52 Chimeric Recombinant Mouse Monoclonal Antibody (YTH 34.5-G2b (Campath-1G))
CD52 항원을 인식하는 Thermo Fisher Scientific의 재조합 마우스 단클론 항체로, 다양한 면역학적 분석(WB, IHC, Flow, ELISA 등)에 사용 가능. 인간 및 영장류 반응성, HEK293 발현 시스템, Protein A 정제, 액상 형태로 제공. 연구용 전용 시약.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (Frozen) (IHC (F)): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- ELISA: Assay-dependent
- Functional Assay: Assay-dependent
- Cytotoxicity Assay (CT): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | YTH 34.5-G2b (Campath-1G) |
| Immunogen | Human peripheral mononuclear cells enriched for T-cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074254 |
Product Specific Information
Specificity: Human CD52 antigen (CAMPATH-1). CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes, and macrophages. It is expressed by most lymphoid-derived malignancies, although expression on myeloma cells is variable.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of immune cells including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in immune regulation and is studied as a therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody used to deplete CD52-expressing immune cells in these conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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