Thermo Fisher Scientific MYCN Monoclonal Antibody (OTI2D5), TrueMAB
MYCN 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 적합하며 Human 및 Rat 시료 반응성. Lyophilized 형태로 제공되어 안정적이며, 재구성 후 conjugation 실험에도 사용 가능. Neuroblastoma 연구용으로 최적화된 고품질 항체.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 229–464 of human MYCN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
N-Myc protein is a member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. It functions similarly to C-Myc in cellular growth and differentiation.
Amplification and overexpression of the MYCN proto-oncogene occur in approximately 20% of neuroblastomas and are associated with advanced disease stage, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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