Thermo Fisher Scientific MYCN Monoclonal Antibody (OTI2A2), TrueMAB
MYCN 단백질을 표적으로 하는 단클론 항체로, 인간 및 랫트 시료에 반응합니다. Western blot에 적합하며, E.coli에서 생산된 인간 MYCN 단백질 조각(aa 229-464)을 면역원으로 사용합니다. 무보존제, 동결건조 형태로 -20°C 보관.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 229–464 of human MYCN produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
N-Myc protein is a member of the MYC family of transcription factors with a basic helix-loop-helix (bHLH) domain. It functions complementarily to C-Myc in cellular growth and differentiation.
MYCN gene amplification and overexpression occur in ~20% of neuroblastomas, correlating with advanced disease stage, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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