
Thermo Fisher Scientific MMP12 Recombinant Rabbit Monoclonal Antibody (2G3)
MMP12 단백질을 인식하는 토끼 단클론 항체로, Western blot과 IHC(P) 분석에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2G3 |
| Immunogen | A synthesized peptide derived from human MMP12 (aa 450–464) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898282 |
Product Specific Information
This antibody has been tested in direct ELISA.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes including arthritis and metastasis.
Most MMPs are secreted as inactive proproteins and activated when cleaved by extracellular proteinases.
The MMP12 enzyme degrades soluble and insoluble elastin and may play a role in aneurysm formation and emphysema development.
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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