Thermo Fisher Scientific PNR Polyclonal Antibody
인간 NR2E3 단백질을 표적으로 하는 Thermo Fisher Scientific의 PNR 폴리클로날 항체. 면역조직화학(IHC) 검증 완료, 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능하며 시각세포 발달 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 7 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from near N-terminus of human NR2E3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551367 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey: 100%
- Gibbon, Marmoset, Mouse, Hamster: 94%
- Bovine: 89%
- Elephant, Pig: 83%
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It plays a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. Homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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