Thermo Fisher Scientific PNR Polyclonal Antibody
NR2E3 단백질을 인식하는 Rabbit Polyclonal Antibody로, 다양한 종(인간, 마우스 등)에 반응합니다. IHC(P)에서 30 µg/mL로 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 30 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Horse, Hamster, Human, Mouse, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from ligand-binding domain of human NR2E3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551368 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Hamster, Elephant, Panda, Bovine, Bat, Horse, Pig (100%)
Marmoset (95%)
Target Information
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development.
It plays a role in determining photoreceptor phenotype during human retinogenesis.
In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration.
A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte.
Two alternatively spliced isoforms have been documented.
NR2E3 is expressed in the retina, and ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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