Thermo Fisher Scientific EAR2 Polyclonal Antibody
Thermo Fisher Scientific의 EAR2 Polyclonal Antibody는 인간 및 비인간 영장류 반응성을 가지며, NR2F6 N-말단 근처 17 아미노산 합성 펩타이드를 면역원으로 사용한 토끼 IgG 폴리클로날 항체입니다. IHC(P) 등 연구용으로 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from near N-terminus of human NR2F6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551370 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Monkey: 100%
- Mouse: 94%
- Dog: 88%
- Opossum: 82%
Target Information
Transcription factor predominantly involved in transcriptional repression.
Binds to promoter/enhancer response elements containing imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings, recognized by other nuclear hormone receptors.
Modulates hormonal responses and represses transcriptional activity of genes such as LHCGR, REN, and OXT.
Regulates thyroid hormone receptor gene activity and inhibits NFATC transcription factor DNA binding, repressing IL-17 expression in Th-17 CD4(+) T cells.
Involved in immunological tolerance, autoimmunity, and development of forebrain circadian clock and locus coeruleus (LC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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