Thermo Fisher Scientific Collagen Type II Polyclonal Antibody, HRP

Thermo Fisher Scientific Collagen Type II Polyclonal Antibody, HRP

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• Restore with 0.05 mL of deionized water (or equivalent).
• For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• Expiration date: one (1) year from date of restoration.

Typically negligible cross-reactivity against other types of collagens was detected by ELISA against purified standards.
This antibody reacts with most mammalian Type II collagens and has negligible cross-reactivity with Type I, III, IV, V, and VI collagens.
Non-specific cross reaction with other human serum proteins or non-collagen extracellular matrix proteins is negligible.

Target Information

COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye.
Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type.
Defects in processing chondrocalcin, a calcium-binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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