Thermo Fisher Scientific Phospho-NMDAR1 (Ser897) Polyclonal Antibody
NMDAR1의 Ser897 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P)에서 사용 가능. Rat, Human, Mouse 반응성. 고순도 정제 및 안정한 PBS/glycerol buffer로 보관 용이.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRIN1 (Accession Q05586), corresponding to amino acid residues around phosphorylated Ser897. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818259 |
Product Specific Information
This antibody detects endogenous levels of NMDAR1 only when phosphorylated at Serine 897.
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. These receptors are heteromeric protein complexes forming ligand-gated ion channels. The subunits play a key role in synaptic plasticity, which underlies memory and learning. Cell-specific factors regulate expression of different isoforms, contributing to subunit functional diversity. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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