
Thermo Fisher Scientific DPYSL5 Monoclonal Antibody (2G4)
DPYSL5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(2G4). Western blot 및 ELISA에 사용 가능. 인간 반응성, Mouse IgG2b 형식. 고순도 친화 크로마토그래피 정제, PBS 용액 형태. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G4 |
| Immunogen | DPYSL5 (NP_064519, 466–564 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SFPDTVYKKL VQREKTLKVR GVDRTPYLGD VAVVVHPGKK EMGTPLADTP TRPVTRHGGM RDLHESSFSL SGSQIDDHVP KRASARILAP PGGRSSGIW
Target Information
The collapsin response mediator protein (CRMP) family (also known as ULIP6) are neurologic proteins involved in growth cone guidance during neural development.
CRMP5 has relatively low sequence homology with other CRMP family members and is expressed in the developing nervous system, peaking during the first postnatal week.
Elevated levels of autoantibody to CRMP5 are linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms.
Autoimmunity against CRMP5 expression (predominantly N-terminal epitopes) is being investigated as an oncological marker in the respiratory system and thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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