Thermo Fisher Scientific DPYSL5 Monoclonal Antibody (2D10)
DPYSL5 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 2D10). Western blot, ICC/IF, ELISA 등 다양한 응용에 적합. 인간 및 랫트 반응성. Affinity chromatography로 정제된 액상 항체로, PBS buffer에 보존.
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- H00056896-M04
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D10 |
| Immunogen | DPYSL5 (AAH02874, 1–564 a.a) full-length recombinant protein with GST tag (GST MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLANSASVRI LIKGDKVVND DCTHEADVYI ENGIIQQVGR ELMIPGGAKV IDATGKLVIP GGIDTSTHFH QTFMNATCVD DFYHGTKAAL VGGTTMIIGH VLPDKETSLV DAYEKCRGLA DPKVCCDYAL HVGITWWAPK VKAEMETLVR EKGVNSFQMF MTYKDLYMLR DSELYQVLHA CKDIGAIARV HAENGELVAE GAKEALDLGI TGPEGIEISR PEELEAEATH RVITIANRTH CPIYLVNVSS ISAGDVIAAA KMQGKVVLAE TTTAHATLTG LHYYHQDWSH AAAYVTVPPL RLDTNTSTYL MSLLANDTLN IVASDHRPFT TKQKAMGKED FTKIPHGVSG VQDRMSVIWE RGVVGGKMDE NRFVAVTSSN AAKLLNLYPR KGRIIPGADA DVVVWDPEAT KTISASTQVQ GGDFNLYENM RCHGVPLVTI SRGRVVYENG VFMCAEGTGK FCPLRSFPDT VYKKLVQREK TLKVRGVDRT PYLGDVAVVV HPGKKEMGTP LADTPTRPVT RHGGMRDLHE SSFSLSGSQI DDHVPERASA RILAPPGGRS SGIW
Target Information
The collapsin response mediator protein (CRMP) family (also referred to as ULIP6) are neurologic proteins that play key roles in growth cone guidance during neural development.
CRMP5 has relatively low sequence homology with other CRMP members and is expressed in the developing nervous system with peak expression during the first postnatal week.
Elevated levels of autoantibody to CRMP5 have been linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms.
Autoimmunity against CRMP5 expression (predominantly N-terminal epitopes) is being investigated as an oncological marker in the respiratory system and thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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