Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (KRT10/844, KRT10/1275)
사이토케라틴 10 단클론 항체로 상피세포 마커 연구에 사용됩니다. 인체 반응성이며 IHC(P) 및 IHC(PFA) 실험에 적합합니다. 단클론(Mouse IgG1, kappa) 형태로 제공되며, 4°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 3858-MSM6-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (KRT10/844, KRT10/1275)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT10/844, KRT10/1275 |
| Immunogen | Recombinant human KRT10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not typically endothelial markers, cytokeratins can be present in some microvascular endothelial cells.
There are at least 20 different cytokeratins (CKs) with molecular weights ranging from 40–70 kDa and isoelectric points between 5–8.5, identifiable via two-dimensional gel electrophoresis. CKs are classified into two main types:
- Type I: Acidic polypeptides
- Type II: Basic polypeptides
All epithelial cells express at least one member of each class. Monoclonal antibodies targeting cytokeratin proteins serve as valuable markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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