Thermo Fisher Scientific Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody (KRT10/844, KRT10/1275)
사이토케라틴 10을 표적하는 단클론 항체로, 상피세포의 수퍼바잘 마커로 사용됩니다. IHC(P) 및 IHC(PFA) 실험에 적합하며, 인간 시료에 반응합니다. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4) 버퍼에 보존제 없이 제공됩니다.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.1–0.2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT10/844, KRT10/1275 |
| Immunogen | Recombinant human KRT10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). Although not typically endothelial markers, some microvascular endothelial cells also express cytokeratins.
At least 20 different cytokeratins (40–70 kDa, pI 5–8.5) can be identified via two-dimensional gel electrophoresis.
Cytokeratins are categorized into two main classes:
- Type I (acidic polypeptides)
- Type II (basic polypeptides)
All epithelial cells express at least one member from each class.
Monoclonal antibodies against cytokeratin proteins serve as useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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