Thermo Fisher Scientific Phospho-DNM1L (Ser637) Polyclonal Antibody
DNM1L 단백질의 Ser637 인산화 부위를 인식하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 액상형, 1 mg/mL 농도, PBS/glycerol buffer에 보존. 세포 내 미토콘드리아 분열 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DNM1L (Accession O00429), corresponding to amino acid residues around phosphorylated Ser637. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815867 |
Product Specific Information
This antibody detects endogenous levels of DRP1 only when phosphorylated at Ser637.
Target Information
DRP1 (Dynamin-related protein 1) is a human mitochondrial GTPase that mediates mitochondrial division in mammalian cells. It plays a crucial role in maintaining mitochondrial fission during steady state and apoptosis. DRP1 is essential for proper mitochondrial distribution; in mutant neurons, mitochondria are largely absent from synapses, providing a tool to study mitochondrial roles in neuronal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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